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In the second half of the book, Dr. Robbins discusses how to address the social and psychological factors leading to HIV and AIDS. He also delves into the diagnostic and treatment options for HIV and AIDS. Indeed, Dr. Robbins provides a sensible, thorough, and especially-considered look at the challenges and treatment options for HIV and AIDS. This book will prove to be an invaluable resource for both HIV-positive and HIV-negative individuals alike.“From the clinical perspective, AIDS is now considered a treatable disease as a result of the advances in drug therapy” (p. 285), and Robbins highlights a number of advancements in this area. For example, the use of protease inhibitors (such as saquinavir, ritonavir, nelfinavir, and amprenavir) as a part of combination therapy is expected to result in lower levels of viral replication with a resultant greater diminution of HIV-associated disease, including AIDS, than were present prior to the introduction of antiretroviral therapy. In addition, the use of highly active antiretroviral therapy (HAART) to suppress viral replication has led to reductions in the morbidity and mortality of HIV-infected individuals. Robbins also addresses the clinical and psychological challenges associated with new viral infections, including the impact of HIV-related peripheral neuropathies and the importance of optimal nutrient and immune function. Most importantly, Robbins highlights the delicate interplay between pathogenic and nonpathogenic HIV variants and the use of antiretroviral drugs in the management of HIV. In the first half of the book, he discusses: many of the clinical, epidemiologic, and molecular aspects of HIV infection. Pathogenesis of the virus and the role of the immune system. The clinical impact of HIV infection on the CNS and on the cardiovascular system. Treatment choices and alternative drug therapies. HIV-related peripheral neuropathies and the impact of antiretroviral drugs. Medical care and the role of preventive medicine in the management of HIV and AIDS. Robbins is an expert in treating HIV-infected individuals, and his insights on the viral and the immune response to HIV are extensive. In particular, Robbins provides the reader with a greater understanding of the nature and care of HIV-infected individuals and the impact of HIV infection on many aspects of life. Robbins’s lucid, clear-cut prose reflects his passion for his subject. He clearly demonstrates the logic of how medical science has advanced, and

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